منابع مشابه
Redox regulated peroxisome homeostasis
Peroxisomes are ubiquitous organelles present in nearly all eukaryotic cells. Conserved functions of peroxisomes encompass beta-oxidation of fatty acids and scavenging of reactive oxygen species generated from diverse peroxisomal metabolic pathways. Peroxisome content, number, and size can change quickly in response to environmental and/or developmental cues. To achieve efficient peroxisome hom...
متن کاملChapter 1 General introduction: Peroxisome homeostasis in Hansenula polymorpha
Peroxisomes are essential organelles in many eukaryotes. Until recently, the main focus of the investigations concerning this important organelle was to understand the biogenesis of the peroxisome (induction, proliferation and matrix protein import). However, when peroxisomes become redundant they are quickly degraded by highly selective processes known as pexophagy. The first molecular studies...
متن کاملYeast Methylotrophy: Metabolism, Gene Regulation and Peroxisome Homeostasis
Eukaryotic methylotrophs, which are able to obtain all the carbon and energy needed for growth from methanol, are restricted to a limited number of yeast species. When these yeasts are grown on methanol as the sole carbon and energy source, the enzymes involved in methanol metabolism are strongly induced, and the membrane-bound organelles, peroxisomes, which contain key enzymes of methanol meta...
متن کاملThe Roles of b-Oxidation and Cofactor Homeostasis in Peroxisome Distribution and Function in Arabidopsis thaliana
Key steps of essential metabolic pathways are housed in plant peroxisomes. We conducted a microscopy-based screen for anomalous distribution of peroxisomally targeted fluorescence in Arabidopsis thaliana. This screen uncovered 34 novel alleles in 15 genes affecting oil body mobilization, fatty acid b-oxidation, the glyoxylate cycle, peroxisome fission, and pexophagy. Partial loss-of-function of...
متن کاملThe Roles of β-Oxidation and Cofactor Homeostasis in Peroxisome Distribution and Function in Arabidopsis thaliana.
Key steps of essential metabolic pathways are housed in plant peroxisomes. We conducted a microscopy-based screen for anomalous distribution of peroxisomally targeted fluorescence in Arabidopsis thaliana This screen uncovered 34 novel alleles in 15 genes affecting oil body mobilization, fatty acid β-oxidation, the glyoxylate cycle, peroxisome fission, and pexophagy. Partial loss-of-function of ...
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ژورنال
عنوان ژورنال: FEMS Yeast Research
سال: 2003
ISSN: 1567-1356
DOI: 10.1016/s1567-1356(03)00070-9